E-ISSN 1858-8360 | ISSN 0256-4408
 

Original Article
Online Published: 27 Jun 2026
 


A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study

Dharmraj Maurya, Ankur Kumar, Anita Mehta, Hirawati Dewal, Neha Srivastava, Ajeet Kumar Yadav.


Abstract
A novel Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) led to Coronavirus Disease 2019 (COVID-19), which is a global health problem, that occurred in waves and resulted in high mortality globally. This is a single-centre retrospective study conducted in a Medical College’s dedicated Covid hospital in India during the first wave (March-November 2020) and second wave (March-May 2021) of COVID-19 pandemic on 104 children below 18 years of age to compare the clinical characteristics and outcome of COVID-19 patients during the first and second waves. During first wave (n=57, 54.8%) majority of children (n=36, 63.16%) were between 5-18 years, but during the second wave (n=47, 62.09%), majority of children (n=29, 61.70%) were below 5 years. Neonates outnumbered during second wave (n=11, 23.4% vs n=1, 1.8%). Asymptomatic patients (n=24, 42.1%) were common during first wave, while severe-grade patients (n=19, 40.4%) were common during second wave. During both the waves, fever and respiratory distress were the common symptoms followed by cough. Respiratory distress (p=0.0003), CRP (p=.008), SPO2 <94% (p=0.00002) and acidosis (p=0.001) were significantly higher during the second wave. Use of steroids and LMW heparin were similar in two waves, but ICU admission (p=0.0031), oxygen via nasal prongs (p=0.0003), use of CPAP/BIPAP (p=0.031), blood and blood products (p=0.044), comorbidity (p=0.017) and mortality (p=0.008) were significantly higher during second wave. ICU admission, use of blood and blood products, mechanical ventilation, comorbidity and mortality were found to be higher during second wave.

Key words: COVID-19, Children, First wave, Second Wave, D-dimer, Serum Ferritin, Procalcitonin, C Reactive Protein, Loss of smell and taste, LMW Heparin, Comorbidity


 
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How to Cite this Article
Pubmed Style

Maurya D, Kumar A, Mehta A, Dewal H, Srivastava N, Yadav AK. A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. Sudan J Paed. Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401


Web Style

Maurya D, Kumar A, Mehta A, Dewal H, Srivastava N, Yadav AK. A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. https://sudanjp.com//?mno=204131 [Access: June 27, 2026]. doi:10.24911/SJP.106-1717338401


AMA (American Medical Association) Style

Maurya D, Kumar A, Mehta A, Dewal H, Srivastava N, Yadav AK. A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. Sudan J Paed. Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401



Vancouver/ICMJE Style

Maurya D, Kumar A, Mehta A, Dewal H, Srivastava N, Yadav AK. A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. Sudan J Paed, [cited June 27, 2026]; Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401



Harvard Style

Maurya, D., Kumar, . A., Mehta, . A., Dewal, . H., Srivastava, . N. & Yadav, . A. K. (0) A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. Sudan J Paed, Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401



Turabian Style

Maurya, Dharmraj, Ankur Kumar, Anita Mehta, Hirawati Dewal, Neha Srivastava, and Ajeet Kumar Yadav. 0. A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. Sudanese Journal of Paediatrics, Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401



Chicago Style

Maurya, Dharmraj, Ankur Kumar, Anita Mehta, Hirawati Dewal, Neha Srivastava, and Ajeet Kumar Yadav. "A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study." Sudanese Journal of Paediatrics Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401



MLA (The Modern Language Association) Style

Maurya, Dharmraj, Ankur Kumar, Anita Mehta, Hirawati Dewal, Neha Srivastava, and Ajeet Kumar Yadav. "A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study." Sudanese Journal of Paediatrics Online First: 27 Jun, 2026. Web. 27 Jun 2026 doi:10.24911/SJP.106-1717338401



APA (American Psychological Association) Style

Maurya, D., Kumar, . A., Mehta, . A., Dewal, . H., Srivastava, . N. & Yadav, . A. K. (0) A Comparative Study of COVID-19 Patients Admitted During First and Second Wave in a Tertiary Care Hospital in Eastern India: A Retrospective Observational Study. Sudanese Journal of Paediatrics, Online First: 27 Jun, 2026. doi:10.24911/SJP.106-1717338401





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