E-ISSN 1858-8360 | ISSN 0256-4408
 

Original Article

Online Publishing Date: 09 / 05 / 2020

 


Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre

Sulafa KM Ali.


Abstract
Sildenafil is a selective pulmonary vasodilator that had been introduced recently for the treatment of pulmonary hypertension. We used Sildenafil (Viagra, Pfizer) in 11 patients with pulmonary hypertension divided into 2 groups. Group 1 were 4 patients without cardiac disease: 3 with primary pulmonary hypertension and one with possible connective tissue disease. Group 2 were 7 patients who had cardiac surgery (6 for congenital heart disease and one for mitral valve replacement).
Results: In all patients there was a significant improvement in clinical and echocardiographic parameters of pulmonary hypertension. The effect was more pronounced in group 2 who were all weaned successfully from Sildenafil without side effects. One patient in Group 1 experienced periods of incoherent speech 18 months after the use of Sildenafil.
Conclusion: Sildenafil is an effective and safe drug for the treatment of pulmonary hypertension especially in post-operative patients.

Key words: Pediatrics


 
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Pubmed Style

Sulafa KM Ali. Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. Sudan J Paed. Online First: 09 May, 2020.


Web Style

Sulafa KM Ali. Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. https://sudanjp.com//?mno=105913 [Access: February 08, 2024].


AMA (American Medical Association) Style

Sulafa KM Ali. Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. Sudan J Paed. Online First: 09 May, 2020.



Vancouver/ICMJE Style

Sulafa KM Ali. Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. Sudan J Paed, [cited February 08, 2024]; Online First: 09 May, 2020.



Harvard Style

Sulafa KM Ali (2007) Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. Sudan J Paed, Online First: 09 May, 2020.



Turabian Style

Sulafa KM Ali. 2007. Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. Sudanese Journal of Paediatrics, Online First: 09 May, 2020.



Chicago Style

Sulafa KM Ali. "Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre." Sudanese Journal of Paediatrics Online First: 09 May, 2020.



MLA (The Modern Language Association) Style

Sulafa KM Ali. "Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre." Sudanese Journal of Paediatrics Online First: 09 May, 2020. Web. 08 Feb 2024



APA (American Psychological Association) Style

Sulafa KM Ali (2007) Use of Sildenafil in the treatment of pulmonary hypertension; Experience of Sudan Heart Centre. Sudanese Journal of Paediatrics, Online First: 09 May, 2020.





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