E-ISSN 1858-8360 | ISSN 0256-4408
 

- 


An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.

Imadeldin M Taj Eldin; Majed M Abdalmutalab; Haydar E Bikir.


Abstract
Haemostasis is the process of forming clots in the walls of damaged blood vessels to prevent abnormal bleeding and to maintain intravascular blood in a fluid state. Fenugreek is largely universal staple herb, popular throughout history and it has been consumed for treatment of different disorders. We aimed to study the possible anticoagulant effect of Fenugreek aqueous extract in vitro by using blood samples of normal individuals. In vitro anticoagulant effects of Fenugreek aqueous extract (5%) in different volumes (25, 50 and 75 μL) were examined in the blood samples of normal individuals by measuring prothrombin time (PT). The aqueous extract of Fenugreek was found to inhibit coagulation process in vitro and significantly prolonged prothrombin time in a dose-dependent manner. Fenugreek aqueous extract in different concentrations inhibits clot formation and increases prothrombin time. Subject to further studies on efficacy and safety, It can well be used, in the future, as a supplementary anticoagulant agent in cardiovascular diseases and to prevent hypercoagulable states.

Key words: Anticoagulant; Fenugreek; Haemostasis; Medicinal plants; Prothrombin time; Sudan


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Imadeldin M Taj Eldin; Majed M Abdalmutalab; Haydar E Bikir
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Eldin IMT, Abdalmutalab MM, Bikir HE. An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. Sudan J Paed. 2013; 13(2): 52-6.


Web Style

Eldin IMT, Abdalmutalab MM, Bikir HE. An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. https://sudanjp.com//?mno=280717 [Access: June 21, 2024].


AMA (American Medical Association) Style

Eldin IMT, Abdalmutalab MM, Bikir HE. An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. Sudan J Paed. 2013; 13(2): 52-6.



Vancouver/ICMJE Style

Eldin IMT, Abdalmutalab MM, Bikir HE. An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. Sudan J Paed. (2013), [cited June 21, 2024]; 13(2): 52-6.



Harvard Style

Eldin, I. M. T., Abdalmutalab, . M. M. & Bikir, . H. E. (2013) An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. Sudan J Paed, 13 (2), 52-6.



Turabian Style

Eldin, Imadeldin M Taj, Majed M Abdalmutalab, and Haydar E Bikir. 2013. An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. Sudanese Journal of Paediatrics, 13 (2), 52-6.



Chicago Style

Eldin, Imadeldin M Taj, Majed M Abdalmutalab, and Haydar E Bikir. "An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.." Sudanese Journal of Paediatrics 13 (2013), 52-6.



MLA (The Modern Language Association) Style

Eldin, Imadeldin M Taj, Majed M Abdalmutalab, and Haydar E Bikir. "An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.." Sudanese Journal of Paediatrics 13.2 (2013), 52-6. Print.



APA (American Psychological Association) Style

Eldin, I. M. T., Abdalmutalab, . M. M. & Bikir, . H. E. (2013) An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.. Sudanese Journal of Paediatrics, 13 (2), 52-6.





Most Viewed Articles
Most Accessed Articles

  • Rheumatic heart disease in North Darfur: an alarmingly high burden and control initiative
    Nagwa Salih, Ishag Eisa, Daresalam Ishag, Intisar Ibrahim, Sulafa Ali
    Sudan J Paed. 2018; 18(1): 24-27
    » Abstract » doi: 10.24911/SJP.2018.1.4

  • Feeding growth restricted premature neonates: a challenging perspective
    Siba Prosad Paul, Emily Natasha Kirkham, Katherine Amy Hawton, Paul Anthony Mannix
    Sudan J Paed. 2018; 18(2): 5-14
    » Abstract » doi: 10.24911/SJP.106-1519511375

  • Congenital brain malformations in Sudanese children: an outpatient-based study
    Inaam Noureldyme Mohammed, Soad Abdalaziz Suliman, Maha A Elseed, Ahlam Abdalrhman Hamed, Mohamed Osman Babiker, Shaimaa Osman Taha
    Sudan J Paed. 2018; 18(1): 48-56
    » Abstract » doi: 10.24911/SJP.2018.1.7

  • Evaluation of Science. [eng]
    Adnan Mahmmood Usmani; Sultan Ayoub Meo
    Sudan J Paed. 2011; 11(1): 6-7
    » Abstract

  • Medical education and services in an extreme environment
    Mustafa Abdalla M. Salih, Mohammed Osman Swar
    Sudan J Paed. 2018; 18(1): 2-5
    » Abstract » doi: 10.24911/SJP.2018.1.1

  • Most Downloaded
    Top Downloaded Articles

  • The role of micronutrients in thyroid dysfunction
    Amir Babiker, Afnan Alawi, Mohsen Al Atawi, Ibrahim Al Alwan
    Sudan J Paed. 2020; 20(1): 13-19
    » Abstract » doi: 10.24911/SJP.106-1587138942

  • Neonatal polycythaemia
    Bashir Abdrhman Bashir, Suhair Abdrahim Othman
    Sudan J Paed. 2019; 19(2): 81-83
    » Abstract » doi: 10.24911/SJP.106-1566075225

  • Relactation in lactation failure and low milk supply
    Anita Mehta, Arvind Kumar Rathi, Komal Prasad Kushwaha, Abhishek Singh
    Sudan J Paed. 2018; 18(1): 39-47
    » Abstract » doi: 10.24911/SJP.2018.1.6

  • Inborn errors of metabolism associated with hyperglycaemic ketoacidosis and diabetes mellitus: narrative review
    Majid Alfadhel, Amir Babiker
    Sudan J Paed. 2018; 18(1): 10-23
    » Abstract » doi: 10.24911/SJP.2018.1.3

  • Anti-diabetic medications: How to make a choice?
    Amir Babiker, Mohammed Al Dubayee
    Sudan J Paed. 2017; 17(2): 11-20
    » Abstract » doi: 10.24911/SJP.2017.2.12