E-ISSN 1858-8360 | ISSN 0256-4408
 

Original Article

Online Publishing Date: 09 / 05 / 2020

 


Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan

Karim-Eldin M. A. Salih, El-Nageeb S. Saeed, Mubarak S. Karsani, Rehab El-Ageb, Salah A. Ibrahim.


Abstract
In the Sudan, acute bacterial meningitis (ABM) remains a major threat for children under five. The objectives of this study were to determine the causative agents of acute bacterial meningitis by using rapid diagnostic techniques and study the short term outcome. During a six-month period, a total of 117 patients clinically diagnosed as ABM in Omdurman Children's Hospital, were investigated using latex agglutination test (serology) and polymerase chain reaction (PCR). The cerebrospinal fluid tested using serology was positive forABM inSO (42.73%) cases of whom 22 (44.0% ), 18 (36.0%) and 10 (20.0%) cases were due to Haemophilius influenzaetype b(Hib), Neisseria meningitides (MCM)and Streptococcus pneumoniae (SPM), respectively. The PCR showed S8 (S4.7%) positive cases of which MCM, Hib and SPM comprised 37 (63.79%), 11 (10.37%) and 10 (9.43%) cases, respectively. The PCR test proved to be a better diagnostic tool particularly for MCM (p<0.001). In Toto, the study showed that the main
causative agents of ABM in children under five were Neisseria meningitides in 51% (n=SS),Haemophilius influenzaetype b in 31% (n=33) and Streptococcus pneumonia in 18% (n=20). Ten of the patients developed neurological complications and three cases died giving a case fatality rate of 2.8%. The need for rapid diagnostic tests to diagnose ABM in order to lower under-S morbidity and mortality cannot be overemphasized.

Key words: Haemophilous inflaenzae type b, meningitis, Niesseria meningitides, Streptococcal pneumoniae meningitis, Sudan.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Karim-Eldin M. A. Salih
Articles by El-Nageeb S. Saeed
Articles by Mubarak S. Karsani
Articles by Rehab El-Ageb
Articles by Salah A. Ibrahim
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Salih KMA, Saeed ES, Karsani MS, El-Ageb R, Ibrahim SA. Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. Sudan J Paed. Online First: 09 May, 2020.


Web Style

Salih KMA, Saeed ES, Karsani MS, El-Ageb R, Ibrahim SA. Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. https://sudanjp.com//?mno=105984 [Access: February 07, 2024].


AMA (American Medical Association) Style

Salih KMA, Saeed ES, Karsani MS, El-Ageb R, Ibrahim SA. Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. Sudan J Paed. Online First: 09 May, 2020.



Vancouver/ICMJE Style

Salih KMA, Saeed ES, Karsani MS, El-Ageb R, Ibrahim SA. Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. Sudan J Paed, [cited February 07, 2024]; Online First: 09 May, 2020.



Harvard Style

Salih, K. M. A., Saeed, . E. S., Karsani, . M. S., El-Ageb, . R. & Ibrahim, . S. A. (2010) Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. Sudan J Paed, Online First: 09 May, 2020.



Turabian Style

Salih, Karim-Eldin M. A., El-Nageeb S. Saeed, Mubarak S. Karsani, Rehab El-Ageb, and Salah A. Ibrahim. 2010. Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. Sudanese Journal of Paediatrics, Online First: 09 May, 2020.



Chicago Style

Salih, Karim-Eldin M. A., El-Nageeb S. Saeed, Mubarak S. Karsani, Rehab El-Ageb, and Salah A. Ibrahim. "Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan." Sudanese Journal of Paediatrics Online First: 09 May, 2020.



MLA (The Modern Language Association) Style

Salih, Karim-Eldin M. A., El-Nageeb S. Saeed, Mubarak S. Karsani, Rehab El-Ageb, and Salah A. Ibrahim. "Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan." Sudanese Journal of Paediatrics Online First: 09 May, 2020. Web. 07 Feb 2024



APA (American Psychological Association) Style

Salih, K. M. A., Saeed, . E. S., Karsani, . M. S., El-Ageb, . R. & Ibrahim, . S. A. (2010) Rapid Test for Diagnosis of Bacterial Meningitis and Short Term Outcome in Children Under Five Years in Omdurman Hospital, Sudan. Sudanese Journal of Paediatrics, Online First: 09 May, 2020.





Most Viewed Articles
Most Accessed Articles

  • Rheumatic heart disease in North Darfur: an alarmingly high burden and control initiative
    Nagwa Salih, Ishag Eisa, Daresalam Ishag, Intisar Ibrahim, Sulafa Ali
    Sudan J Paed. 2018; 18(1): 24-27
    » Abstract » doi: 10.24911/SJP.2018.1.4

  • Feeding growth restricted premature neonates: a challenging perspective
    Siba Prosad Paul, Emily Natasha Kirkham, Katherine Amy Hawton, Paul Anthony Mannix
    Sudan J Paed. 2018; 18(2): 5-14
    » Abstract » doi: 10.24911/SJP.106-1519511375

  • Congenital brain malformations in Sudanese children: an outpatient-based study
    Inaam Noureldyme Mohammed, Soad Abdalaziz Suliman, Maha A Elseed, Ahlam Abdalrhman Hamed, Mohamed Osman Babiker, Shaimaa Osman Taha
    Sudan J Paed. 2018; 18(1): 48-56
    » Abstract » doi: 10.24911/SJP.2018.1.7

  • Evaluation of Science. [eng]
    Adnan Mahmmood Usmani; Sultan Ayoub Meo
    Sudan J Paed. 2011; 11(1): 6-7
    » Abstract

  • Medical education and services in an extreme environment
    Mustafa Abdalla M. Salih, Mohammed Osman Swar
    Sudan J Paed. 2018; 18(1): 2-5
    » Abstract » doi: 10.24911/SJP.2018.1.1

  • Most Downloaded
    Top Downloaded Articles

  • The role of micronutrients in thyroid dysfunction
    Amir Babiker, Afnan Alawi, Mohsen Al Atawi, Ibrahim Al Alwan
    Sudan J Paed. 2020; 20(1): 13-19
    » Abstract » doi: 10.24911/SJP.106-1587138942

  • Why mothers are not exclusively breast feeding their babies till 6 months of age? Knowledge and practices data from two large cities of the Kingdom of Saudi Arabia
    Hafsa Raheel, Shabana Tharkar
    Sudan J Paed. 2018; 18(1): 28-38
    » Abstract » doi: 10.24911/SJP.2018.1.5

  • Relactation in lactation failure and low milk supply
    Anita Mehta, Arvind Kumar Rathi, Komal Prasad Kushwaha, Abhishek Singh
    Sudan J Paed. 2018; 18(1): 39-47
    » Abstract » doi: 10.24911/SJP.2018.1.6

  • Inborn errors of metabolism associated with hyperglycaemic ketoacidosis and diabetes mellitus: narrative review
    Majid Alfadhel, Amir Babiker
    Sudan J Paed. 2018; 18(1): 10-23
    » Abstract » doi: 10.24911/SJP.2018.1.3

  • Neonatal polycythaemia
    Bashir Abdrhman Bashir, Suhair Abdrahim Othman
    Sudan J Paed. 2019; 19(2): 81-83
    » Abstract » doi: 10.24911/SJP.106-1566075225

  • Most Cited Articles
    Most Cited Articles

  • Anti-diabetic medications: How to make a choice?
    Amir Babiker, Mohammed Al Dubayee
    Sudan J Paed. 2017; 17(2): 11-20
    » Abstract » doi: 10.24911/SJP.2017.2.12
    Cited : 8 times [Click to see citing articles]

  • Commitment to the wellbeing of children worldwide. [eng]
    Mustafa Abdalla M Salih; Satti Abdelrahim Satti
    Sudan J Paed. 2011; 11(2): 4-5
    » Abstract
    Cited : 4 times [Click to see citing articles]

  • Pattern of malaria in hospitalized children in Khartoum state
    Hasan Awadalla Hashim, Eltigani Mohamed Ahmed Ali
    Sudan J Paed. 2017; 17(2): 35-41
    » Abstract » doi: 10.24911/SJP.2017.2.4
    Cited : 4 times [Click to see citing articles]

  • The role of micronutrients in thyroid dysfunction
    Amir Babiker, Afnan Alawi, Mohsen Al Atawi, Ibrahim Al Alwan
    Sudan J Paed. 2020; 20(1): 13-19
    » Abstract » doi: 10.24911/SJP.106-1587138942
    Cited : 4 times [Click to see citing articles]

  • Broad beans ( Vicia faba ) and the potential to protect from COVID-19 coronavirus infection
    Mutasim I. Khalil, Mustafa A. Salih, Ali A. Mustafa
    Sudan J Paed. 2020; 20(1): 10-12
    » Abstract » doi: 10.24911/SJP.1061585398078
    Cited : 4 times [Click to see citing articles]